Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 6/20 | 1.00 |
| ▸ | AR | P10275 | 8/20 | 0.64 |
| ▸ | PARP1 | P09874 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4713938 | 1.00 | PRMT5 (1.00) | PRMT5ARPARP1LMNAPOLB | |
| Hydrochloric Acid SCHEMBL6342244 | 0.98 | PRMT5 (0.96) | PRMT5ARPARP1LMNAPOLB | |
| Hydrochloric Acid SCHEMBL13721136 | 0.96 | PRMT5 (0.93) | PRMT5ARPARP1LMNAPOLB | |
| SCHEMBL23909125 | 0.81 | PRMT5 (0.68) | PRMT5ARPARP1LMNAPOLB | |
| SCHEMBL29404780 | 0.81 | PRMT5 (0.68) | PRMT5ARPARP1LMNAPOLB | |
| SCHEMBL7462930 | 0.81 | PRMT5 (0.68) | PRMT5ARPARP1LMNAPOLB | |
| SCHEMBL4817305 | 0.81 | PRMT5 (0.68) | PRMT5ARPARP1LMNAPOLB | |
| SCHEMBL6328127 | 0.81 | PRMT5 (0.68) | PRMT5ARPARP1LMNAPOLB | |
| SCHEMBL21575704 | 0.81 | PRMT5 (0.68) | PRMT5ARPARP1LMNAPOLB | |
| SCHEMBL30231202 | 0.81 | PRMT5 (0.68) | PRMT5ARPARP1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665337-A1 | PRMT5 INHIBITOR FOR USE IN CANCER THERAPY | Astrazeneca AB (SE) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024249763-A2 | PRMT5 SYNTHETIC LETHAL INHIBITORS TARGETING MTAP DELETED CANCERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-12-05 | — | — | WO | disclosed |
| WO-2024249931-A1 | PRMT5 INHIBITORS TARGETING MTAP DELETED CANCERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-12-05 | — | — | WO | disclosed |
| WO-2024170488-A1 | PRMT5 INHIBITOR FOR USE IN CANCER THERAPY | ASTRAZENECA AB (SE) | 2024-08-22 | — | — | WO | disclosed |