Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 3/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 1/20 | 1.00 |
| ▸ | NPC1 | O15118 | 16/20 | 0.69 |
| ▸ | RAB9A | P51151 | 15/20 | 0.69 |
| ▸ | MEN1 | O00255 | 11/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.67 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.67 |
| ▸ | RELA | Q04206 | 4/20 | 0.67 |
| ▸ | TP53 | P04637 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | MECP2 | P51608 | 1/20 | 0.63 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.63 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.63 |
| ▸ | MBD2 | Q9UBB5 | 1/20 | 0.63 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366994 | 1.00 | GRM4 (1.00) | GRM4KCNH2NPC1RAB9AMEN1 | |
| SCHEMBL371225 | 0.84 | GRM4 (0.72) | GRM4KCNH2NPC1RAB9AMEN1 | |
| SCHEMBL7552748 | 0.83 | NPC1 (0.91) | GRM4KCNH2NPC1RAB9AMEN1 | |
| SCHEMBL16217145 | 0.82 | NPC1 (1.00) | GRM4KCNH2NPC1RAB9AMEN1 | |
| Bromide SCHEMBL7669000 | 0.82 | NPC1 (0.88) | GRM4KCNH2NPC1RAB9AMEN1 | |
| SCHEMBL367354 | 0.81 | GRM4 (0.68) | GRM4KCNH2NPC1RAB9AMEN1 | |
| SCHEMBL368073 | 0.81 | GRM4 (0.68) | GRM4KCNH2NPC1RAB9AMEN1 | |
| SCHEMBL365863 | 0.81 | NPC1 (0.68) | GRM4KCNH2NPC1RAB9AMEN1 | |
| SCHEMBL12296219 | 0.81 | NPC1 (1.00) | GRM4KCNH2NPC1RAB9AMEN1 | |
| SCHEMBL18029575 | 0.80 | NPC1 (0.94) | GRM4KCNH2NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |