Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 14/20 | 0.49 |
| ▸ | CCNA2 | P20248 | 12/20 | 0.49 |
| ▸ | AURKA | O14965 | 6/20 | 0.49 |
| ▸ | CDK4 | P11802 | 5/20 | 0.49 |
| ▸ | CCND3 | P30281 | 5/20 | 0.49 |
| ▸ | CDK6 | Q00534 | 5/20 | 0.49 |
| ▸ | CCNA1 | P78396 | 7/20 | 0.47 |
| ▸ | PLK1 | P53350 | 6/20 | 0.44 |
| ▸ | PLK3 | Q9H4B4 | 4/20 | 0.44 |
| ▸ | PLK2 | Q9NYY3 | 3/20 | 0.44 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.44 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL526058 | 1.00 | CDK2 (0.49) | CDK2CCNA2AURKACDK4CCND3 | |
| SCHEMBL526265 | 0.88 | CDK2 (0.49) | CDK2CCNA2AURKACDK4CCND3 | |
| SCHEMBL9940553 | 0.84 | CDK2 (0.69) | CDK2CCNA2AURKACDK4CCND3 | |
| Trifluoroacetic Acid SCHEMBL14990435 | 0.84 | CCNA2 (0.45) | CDK2CCNA2AURKACDK4CCND3 | |
| SCHEMBL525847 | 0.81 | CDK2 (0.73) | CDK2CCNA2AURKACDK4CCND3 | |
| SCHEMBL9940579 | 0.76 | CDK2 (0.70) | CDK2CCNA2AURKACDK4CCND3 | |
| SCHEMBL526773 | 0.76 | PLK1 (0.76) | CDK2CCNA2CCNA1PLK1PLK3 | |
| SCHEMBL10092919 | 0.74 | CHEK1 (0.38) | CDK2CCNA2AURKACDK4CCND3 | |
| SCHEMBL10092916 | 0.73 | PLK1 (0.68) | CDK2CCNA2CCNA1PLK1PLK3 | |
| SCHEMBL525992 | 0.71 | CDK2 (0.59) | CDK2CCNA2AURKACDK4CCND3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |