SCHEMBL31060352

SCHEMBL31060352

COc1cc2cc(-c3ccc([N+](=O)[O-])cc3)cnc2cc1OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDGFRB P09619 20/20 1.00
PDGFRA P16234 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2203575 0.83 PDGFRB (0.70) PDGFRBPDGFRA
SCHEMBL8501467 0.80 PDGFRB (1.00) PDGFRBPDGFRA
SCHEMBL8501509 0.80 PDGFRB (0.97) PDGFRBPDGFRA
SCHEMBL31060975 0.80 PDGFRB (1.00) PDGFRBPDGFRA
SCHEMBL31060179 0.79 PDGFRB (1.00) PDGFRBPDGFRA
SCHEMBL31060849 0.79 PDGFRB (1.00) PDGFRBPDGFRA
SCHEMBL8177777 0.78 PDGFRB (1.00) PDGFRBPDGFRA
SCHEMBL31060782 0.78 PDGFRB (1.00) PDGFRBPDGFRA
SCHEMBL31061185 0.77 PDGFRB (1.00) PDGFRBPDGFRA
SCHEMBL8172493 0.77 PDGFRB (1.00) PDGFRBPDGFRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4662319-A2 PERSONALIZED CRISPR PROFILING FOR CANCER Integrate Bioscience LLC (US) 2025-12-17 EP disclosed
WO-2024168301-A2 PERSONALIZED CRISPR PROFILING FOR CANCER FUNCTION ONCOLOGY, INC. (US) 2024-08-15 WO disclosed