Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 19/20 | 0.57 |
| ▸ | PDCD1 | Q15116 | 6/20 | 0.55 |
| ▸ | NT5E | P21589 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22401056 | 0.85 | CD274 (0.55) | CD274PDCD1 | |
| SCHEMBL20763871 | 0.82 | CD274 (0.63) | CD274PDCD1NT5E | |
| SCHEMBL16555129 | 0.81 | CD274 (0.61) | CD274PDCD1NT5E | |
| SCHEMBL19788562 | 0.79 | CD274 (0.70) | CD274PDCD1 | |
| SCHEMBL29271887 | 0.79 | CD274 (0.63) | CD274PDCD1 | |
| SCHEMBL17898328 | 0.78 | CD274 (0.65) | CD274PDCD1 | |
| SCHEMBL24822011 | 0.78 | CD274 (0.61) | CD274PDCD1 | |
| SCHEMBL16554533 | 0.77 | CD274 (0.67) | CD274PDCD1 | |
| SCHEMBL23495003 | 0.77 | CD274 (0.49) | CD274PDCD1 | |
| SCHEMBL24822304 | 0.77 | CD274 (0.67) | CD274PDCD1NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |