Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.72 |
| ▸ | GAK | O14976 | 1/20 | 0.72 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.72 |
| ▸ | ULK1 | O75385 | 1/20 | 0.72 |
| ▸ | STK10 | O94804 | 1/20 | 0.72 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.72 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.72 |
| ▸ | LATS1 | O95835 | 1/20 | 0.72 |
| ▸ | PAK4 | O96013 | 1/20 | 0.72 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.72 |
| ▸ | LCK | P06239 | 1/20 | 0.72 |
| ▸ | CDK1 | P06493 | 1/20 | 0.72 |
| ▸ | APRT | P07741 | 1/20 | 0.72 |
| ▸ | RET | P07949 | 1/20 | 0.72 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.72 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.72 |
| ▸ | NQO2 | P16083 | 1/20 | 0.72 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.72 |
| ▸ | FECH | P22830 | 1/20 | 0.72 |
| ▸ | CDK2 | P24941 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL859537 | 1.00 | IRAK4 (0.72) | IRAK4GAKRIPK2ULK1STK10 | |
| SCHEMBL29678517 | 1.00 | IRAK4 (0.72) | IRAK4GAKRIPK2ULK1STK10 | |
| SCHEMBL5766267 | 0.95 | IRAK4 (0.66) | IRAK4GAKRIPK2ULK1STK10 | |
| SCHEMBL5764297 | 0.95 | IRAK4 (0.66) | IRAK4GAKRIPK2ULK1STK10 | |
| SCHEMBL5766257 | 0.95 | IRAK4 (0.66) | IRAK4GAKRIPK2ULK1STK10 | |
| SCHEMBL5764257 | 0.91 | IRAK4 (0.61) | IRAK4GAKRIPK2ULK1STK10 | |
| SCHEMBL5764385 | 0.91 | IRAK4 (0.61) | IRAK4GAKRIPK2ULK1STK10 | |
| SCHEMBL5764259 | 0.90 | IRAK4 (0.60) | IRAK4GAKRIPK2ULK1STK10 | |
| SCHEMBL5763184 | 0.90 | IRAK4 (0.71) | IRAK4GAKRIPK2ULK1STK10 | |
| SCHEMBL5766337 | 0.90 | IRAK4 (0.71) | IRAK4GAKRIPK2ULK1STK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |
| WO-2024151804-A2 | METHODS AND MATERIALS FOR GENERATING STEM CELL-DERIVED ENDOCRINE CELL TYPES | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2024-07-18 | — | — | WO | disclosed |