Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 13/20 | 0.97 |
| ▸ | FLT1 | P17948 | 11/20 | 0.97 |
| ▸ | FLT4 | P35916 | 11/20 | 0.97 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.59 |
| ▸ | IMPDH2 | P12268 | 4/20 | 0.58 |
| ▸ | VCP | P55072 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5232183 | 1.00 | KDR (0.97) | KDRFLT1FLT4P2RY1IMPDH2 | |
| SCHEMBL5481691 | 0.85 | KDR (0.73) | KDRFLT1FLT4IMPDH2VCP | |
| SCHEMBL5184593 | 0.81 | KDR (0.67) | KDRFLT1FLT4IMPDH2 | |
| SCHEMBL5481859 | 0.80 | KDR (0.66) | KDRFLT1FLT4 | |
| SCHEMBL5480404 | 0.80 | KDR (0.97) | KDRFLT1FLT4IMPDH2VCP | |
| Gw627512B SCHEMBL5477421 | 0.80 | KDR (1.00) | KDRFLT1FLT4IMPDH2VCP | |
| SCHEMBL5468589 | 0.79 | KDR (1.00) | KDRFLT1FLT4 | |
| Gw631581B SCHEMBL5478552 | 0.79 | KDR (1.00) | KDRFLT1FLT4IMPDH2VCP | |
| SCHEMBL5469555 | 0.78 | KDR (0.63) | KDRFLT1FLT4IMPDH2VCP | |
| SCHEMBL20703563 | 0.77 | KDR (0.96) | KDRFLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |