Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 8/20 | 1.00 |
| ▸ | HPGD | P15428 | 1/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | MMP13 | P45452 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.61 |
| ▸ | PPARG | P37231 | 4/20 | 0.61 |
| ▸ | PPARA | Q07869 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | LTA4H | P09960 | 1/20 | 0.60 |
| ▸ | LSS | P48449 | 1/20 | 0.60 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.57 |
| ▸ | PPARD | Q03181 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2634030 | 0.87 | MAPK14 (0.76) | MAPK14LMNAEPHX2PPARGPPARA | |
| SCHEMBL11979758 | 0.87 | MAPK14 (0.76) | MAPK14HPGDLMNAMMP13EPHX2 | |
| SCHEMBL5709300 | 0.87 | HPGD (0.84) | MAPK14HPGDCYP3A4LMNAHTT | |
| SCHEMBL8738317 | 0.87 | HPGD (0.97) | MAPK14HPGDCYP3A4LMNAHTT | |
| SCHEMBL6257688 | 0.86 | MAPK14 (0.84) | MAPK14HPGDCYP3A4LMNAHTT | |
| SCHEMBL4615722 | 0.85 | MAPK14 (0.74) | MAPK14HPGDSMN1; SMN2EPHX2PPARG | |
| SCHEMBL2471470 | 0.84 | MAPK14 (0.71) | MAPK14HPGDCYP3A4LMNAHTT | |
| SCHEMBL6141262 | 0.83 | HPGD (0.78) | MAPK14HPGDCYP3A4LMNAHTT | |
| SCHEMBL27600905 | 0.83 | HPGD (0.78) | MAPK14HPGDCYP3A4LMNAHTT | |
| SCHEMBL31061058 | 0.83 | MAPK14 (1.00) | MAPK14HPGDCYP3A4LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |