Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 18/20 | 1.00 |
| ▸ | PLK3 | Q9H4B4 | 15/20 | 1.00 |
| ▸ | NEK2 | P51955 | 6/20 | 1.00 |
| ▸ | PIK3CD | O00329 | 2/20 | 1.00 |
| ▸ | NUAK1 | O60285 | 2/20 | 1.00 |
| ▸ | PDGFRB | P09619 | 2/20 | 1.00 |
| ▸ | PIM1 | P11309 | 2/20 | 1.00 |
| ▸ | KDR | P35968 | 2/20 | 1.00 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.81 |
| ▸ | CDK2 | P24941 | 1/20 | 0.66 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gsk-579289A SCHEMBL13206401 | 1.00 | PLK1 (1.00) | PLK1PLK3NEK2PIK3CDNUAK1 | |
| Gsk-579289A SCHEMBL2989105 | 1.00 | PLK1 (1.00) | PLK1PLK3NEK2PIK3CDNUAK1 | |
| SCHEMBL2986963 | 0.93 | PLK1 (0.88) | PLK1PLK3NEK2PIK3CDNUAK1 | |
| SCHEMBL4404485 | 0.92 | PLK1 (0.85) | PLK1PLK3NEK2PIK3CDNUAK1 | |
| SCHEMBL2986655 | 0.92 | PLK1 (0.85) | PLK1PLK3NEK2PIK3CDNUAK1 | |
| SCHEMBL4398348 | 0.92 | PLK1 (0.85) | PLK1PLK3NEK2PIK3CDNUAK1 | |
| SCHEMBL4398344 | 0.92 | PLK1 (0.85) | PLK1PLK3NEK2PIK3CDNUAK1 | |
| SCHEMBL4398413 | 0.92 | PLK1 (0.84) | PLK1PLK3NEK2PIK3CDNUAK1 | |
| SCHEMBL2977601 | 0.91 | PLK1 (0.84) | PLK1PLK3NEK2PIK3CDNUAK1 | |
| SCHEMBL13206399 | 0.91 | PLK1 (0.84) | PLK1PLK3NEK2PIK3CDNUAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |