Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 20/20 | 0.78 |
| ▸ | DYRK1B | Q9Y463 | 15/20 | 0.78 |
| ▸ | GSK3A | P49840 | 2/20 | 0.62 |
| ▸ | GSK3B | P49841 | 2/20 | 0.62 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.60 |
| ▸ | CDK1 | P06493 | 1/20 | 0.60 |
| ▸ | CDK4 | P11802 | 1/20 | 0.60 |
| ▸ | CDK2 | P24941 | 1/20 | 0.60 |
| ▸ | CLK1 | P49759 | 1/20 | 0.60 |
| ▸ | CLK2 | P49760 | 1/20 | 0.60 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.60 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14733448 | 0.88 | DYRK1A (1.00) | DYRK1ADYRK1BGSK3AGSK3BDYRK3 | |
| SCHEMBL17060589 | 0.85 | DYRK1A (0.77) | DYRK1ADYRK1BGSK3AGSK3B | |
| SCHEMBL14733490 | 0.79 | DYRK1A (0.61) | DYRK1ADYRK1BGSK3AGSK3BDYRK3 | |
| SCHEMBL16037427 | 0.78 | DYRK1A (1.00) | DYRK1ADYRK1BGSK3AGSK3B | |
| SCHEMBL14733520 | 0.77 | DYRK1A (1.00) | DYRK1ADYRK1BGSK3AGSK3B | |
| SCHEMBL14733511 | 0.77 | DYRK1A (1.00) | DYRK1ADYRK1BGSK3AGSK3B | |
| SCHEMBL14733540 | 0.76 | DYRK1A (1.00) | DYRK1ADYRK1BGSK3AGSK3B | |
| SCHEMBL14733556 | 0.76 | DYRK1A (1.00) | DYRK1ADYRK1BGSK3AGSK3BDYRK3 | |
| SCHEMBL14733539 | 0.76 | DYRK1A (1.00) | DYRK1ADYRK1BGSK3AGSK3BDYRK3 | |
| SCHEMBL14733469 | 0.76 | DYRK1A (1.00) | DYRK1ADYRK1BGSK3AGSK3BDYRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |