Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 12/20 | 0.59 |
| ▸ | EGFR | P00533 | 10/20 | 0.59 |
| ▸ | KIT | P10721 | 2/20 | 0.57 |
| ▸ | ABL1 | P00519 | 6/20 | 0.57 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | FLT3 | P36888 | 1/20 | 0.57 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | BCR | P11274 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15859828 | 1.00 | BRAF (0.59) | BRAFEGFRKITABL1FGFR1 | |
| SCHEMBL15859861 | 0.95 | BRAF (0.60) | BRAFEGFRKITABL1FGFR1 | |
| SCHEMBL15859803 | 0.94 | BRAF (0.59) | BRAFEGFRKITABL1FGFR1 | |
| SCHEMBL15859903 | 0.93 | EGFR (0.60) | BRAFEGFRKITABL1FGFR1 | |
| SCHEMBL17311263 | 0.92 | BRAF (0.57) | BRAFEGFRKITABL1FGFR1 | |
| SCHEMBL15859829 | 0.92 | BRAF (0.57) | BRAFEGFRKITABL1FGFR1 | |
| SCHEMBL15860017 | 0.91 | BRAF (0.49) | BRAFEGFRKITABL1FGFR1 | |
| SCHEMBL17311270 | 0.90 | EGFR (0.55) | BRAFEGFRKITABL1FGFR1 | |
| SCHEMBL15859831 | 0.90 | BRAF (0.61) | BRAFEGFRKITABL1FGFR1 | |
| SCHEMBL17311287 | 0.90 | BRAF (0.54) | BRAFEGFRKITABL1FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |