SCHEMBL31060971

SCHEMBL31060971

COC(=O)c1c(Cc2ccc(C(=O)NCCO)cc2)c(=O)c2ccc(Cl)cc2n1-c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPK8 P45983 20/20 1.00
MAPK9 P45984 6/20 1.00
MAPK10 P53779 3/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL848656 1.00 MAPK8 (1.00) MAPK8MAPK9MAPK10
SCHEMBL848193 0.92 MAPK8 (0.85) MAPK8MAPK9MAPK10
SCHEMBL847361 0.91 MAPK8 (1.00) MAPK8MAPK9MAPK10
SCHEMBL848062 0.91 MAPK8 (0.84) MAPK8MAPK9MAPK10
SCHEMBL848733 0.91 MAPK8 (0.83) MAPK8MAPK9MAPK10
SCHEMBL847836 0.91 MAPK8 (0.83) MAPK8MAPK9MAPK10
SCHEMBL847906 0.90 MAPK8 (0.85) MAPK8MAPK9MAPK10
SCHEMBL849020 0.89 MAPK8 (0.89) MAPK8MAPK9MAPK10
SCHEMBL848469 0.89 MAPK8 (0.80) MAPK8MAPK9MAPK10
SCHEMBL849713 0.89 MAPK8 (0.79) MAPK8MAPK9MAPK10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4662319-A2 PERSONALIZED CRISPR PROFILING FOR CANCER Integrate Bioscience LLC (US) 2025-12-17 EP disclosed
WO-2024168301-A2 PERSONALIZED CRISPR PROFILING FOR CANCER FUNCTION ONCOLOGY, INC. (US) 2024-08-15 WO disclosed