Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K11 | Q16584 | 13/20 | 1.00 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 1.00 |
| ▸ | KIT | P10721 | 4/20 | 0.74 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.66 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.66 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | CLK1 | P49759 | 1/20 | 0.63 |
| ▸ | BRD4 | O60885 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL722870 | 1.00 | MAP3K11 (1.00) | MAP3K11LRRK2KITDYRK1ACYP3A4 | |
| SCHEMBL720862 | 0.90 | MAP3K11 (1.00) | MAP3K11LRRK2KITDYRK1ACYP3A4 | |
| SCHEMBL724259 | 0.88 | MAP3K11 (0.83) | MAP3K11LRRK2KITDYRK1ACYP3A4 | |
| SCHEMBL27841169 | 0.85 | MAP3K11 (0.83) | MAP3K11LRRK2KITDYRK1ACYP3A4 | |
| SCHEMBL723789 | 0.85 | MAP3K11 (1.00) | MAP3K11LRRK2KITDYRK1ACYP3A4 | |
| SCHEMBL721794 | 0.85 | MAP3K11 (1.00) | MAP3K11LRRK2KITDYRK1ACYP3A4 | |
| SCHEMBL12763559 | 0.83 | MAP3K11 (0.76) | MAP3K11LRRK2KITDYRK1ACYP3A4 | |
| SCHEMBL720152 | 0.82 | MAP3K11 (0.70) | MAP3K11LRRK2KITDYRK1ACYP3A4 | |
| SCHEMBL18136450 | 0.82 | MAP3K11 (0.72) | MAP3K11LRRK2KITDYRK1ACYP3A4 | |
| SCHEMBL722517 | 0.82 | MAP3K11 (0.79) | MAP3K11LRRK2KITDYRK1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |