SCHEMBL31061547

SCHEMBL31061547

Cc1cc(C)c(CNC(=O)c2cc(-c3ccc(N4CCN(CCNC(=O)CC56CC7CC(CC(C7)C5)C6)CC4)nc3)cc3c2cnn3C(C)C)c(=O)[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ EZH2 Q15910 5/20 1.00
▸ EZH1 Q92800 2/20 0.73
▸ EED O75530 1/20 0.73
▸ RBBP4 Q09028 1/20 0.73
▸ SUZ12 Q15022 1/20 0.73
▸ RBBP7 Q16576 1/20 0.73
▸ AEBP2 Q6ZN18 1/20 0.73
▸ HDAC6 Q9UBN7 15/20 0.73
▸ HDAC1 Q13547 11/20 0.72
▸ HDAC4 P56524 1/20 0.66
▸ HDAC7 Q8WUI4 1/20 0.66
▸ HDAC2 Q92769 1/20 0.66
▸ HDAC10 Q969S8 1/20 0.66
▸ HDAC11 Q96DB2 1/20 0.66
▸ HDAC8 Q9BY41 1/20 0.66
▸ HDAC9 Q9UKV0 1/20 0.66
▸ HDAC5 Q9UQL6 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29649766 1.00 EZH2 (1.00) EZH2EZH1EEDRBBP4SUZ12
SCHEMBL21271666 1.00 EZH2 (1.00) EZH2EZH1EEDRBBP4SUZ12
SCHEMBL21271681 0.97 EZH2 (0.93) EZH2EZH1EEDRBBP4SUZ12
SCHEMBL30122881 0.97 EZH2 (0.93) EZH2EZH1EEDRBBP4SUZ12
SCHEMBL30123033 0.94 EZH2 (0.89) EZH2EZH1EEDRBBP4SUZ12
SCHEMBL21271670 0.94 EZH2 (0.89) EZH2EZH1EEDRBBP4SUZ12
SCHEMBL21271679 0.93 EZH2 (0.87) EZH2EZH1EEDRBBP4SUZ12
SCHEMBL28995994 0.93 EZH2 (0.87) EZH2EZH1EEDRBBP4SUZ12
SCHEMBL30122737 0.93 EZH2 (0.87) EZH2EZH1EEDRBBP4SUZ12
SCHEMBL21271631 0.93 EZH2 (0.87) EZH2EZH1EEDRBBP4SUZ12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4662319-A2 PERSONALIZED CRISPR PROFILING FOR CANCER Integrate Bioscience LLC (US) 2025-12-17 — — EP disclosed
WO-2024168301-A2 PERSONALIZED CRISPR PROFILING FOR CANCER FUNCTION ONCOLOGY, INC. (US) 2024-08-15 — — WO disclosed
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