Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31063417 | 1.00 | PRMT5 (0.43) | PRMT5WDR77PIK3CDMEN1ALDH1A1 | |
| SCHEMBL21780530 | 0.96 | PRMT5 (0.42) | PRMT5WDR77PIK3CDMEN1ALDH1A1 | |
| SCHEMBL21784674 | 0.96 | PRMT5 (0.42) | PRMT5WDR77PIK3CDMEN1ALDH1A1 | |
| SCHEMBL31063081 | 0.95 | PRMT5 (0.42) | PRMT5WDR77PIK3CDMEN1ALDH1A1 | |
| SCHEMBL21767761 | 0.92 | PRMT5 (0.47) | PRMT5WDR77PIK3CDMEN1ALDH1A1 | |
| SCHEMBL21777184 | 0.92 | PRMT5 (0.47) | PRMT5WDR77PIK3CDMEN1ALDH1A1 | |
| SCHEMBL21767763 | 0.92 | PRMT5 (0.47) | PRMT5WDR77PIK3CDMEN1ALDH1A1 | |
| SCHEMBL31618501 | 0.92 | HPGD (0.42) | PRMT5WDR77PIK3CDMEN1ALDH1A1 | |
| SCHEMBL31618494 | 0.92 | HPGD (0.42) | PRMT5WDR77PIK3CDMEN1ALDH1A1 | |
| SCHEMBL20140740 | 0.90 | NR1H2 (0.43) | PRMT5WDR77PIK3CDMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665339-A1 | INHIBITING ALPHA V BETA 8 INTEGRIN | Morphic Therapeutic, Inc. (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024173570-A1 | INHIBITING αvβ8 INTEGRIN | MORPHIC THERAPEUTIC, INC. (US) | 2024-08-22 | — | — | WO | disclosed |