Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 20/20 | 0.73 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.71 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.71 |
| ▸ | PDE2A | O00408 | 1/20 | 0.71 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.71 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.71 |
| ▸ | PDE6D | O43924 | 1/20 | 0.71 |
| ▸ | PDE8A | O60658 | 1/20 | 0.71 |
| ▸ | PDE9A | O76083 | 1/20 | 0.71 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | HTR1A | P08908 | 1/20 | 0.71 |
| ▸ | PDE6A | P16499 | 1/20 | 0.71 |
| ▸ | PDE6G | P18545 | 1/20 | 0.71 |
| ▸ | PDE4A | P27815 | 1/20 | 0.71 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.71 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.71 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.71 |
| ▸ | PDE6B | P35913 | 1/20 | 0.71 |
| ▸ | PDE6C | P51160 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21995481 | 1.00 | PDE5A (0.73) | PDE5APDE3BPDE3APDE2AABCC4 | |
| SCHEMBL21995384 | 1.00 | PDE5A (0.73) | PDE5APDE3BPDE3APDE2AABCC4 | |
| SCHEMBL21995385 | 1.00 | PDE5A (0.73) | PDE5APDE3BPDE3APDE2AABCC4 | |
| SCHEMBL31064826 | 1.00 | PDE5A (0.73) | PDE5APDE3BPDE3APDE2AABCC4 | |
| SCHEMBL21995323 | 0.94 | PDE5A (0.73) | PDE5APDE3BPDE3APDE2AABCC4 | |
| SCHEMBL21995286 | 0.94 | PDE5A (0.72) | PDE5APDE3BPDE3APDE2AABCC4 | |
| SCHEMBL29440268 | 0.94 | PDE5A (0.72) | PDE5APDE3BPDE3APDE2AABCC4 | |
| SCHEMBL21995190 | 0.92 | PDE5A (0.72) | PDE5APDE3BPDE3APDE2AABCC4 | |
| SCHEMBL21995435 | 0.92 | PDE5A (0.72) | PDE5APDE3BPDE3APDE2AABCC4 | |
| SCHEMBL21995187 | 0.92 | PDE5A (0.72) | PDE5APDE3BPDE3APDE2AABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166157-B | Double-acting mode soluble guanylate cyclase activators and phosphodiesterase inhibitors and uses thereof | 托帕杜制药公司 | 2024-08-27 | — | — | CN | claimed |
| CN-113166157-B | Double-acting mode soluble guanylate cyclase activators and phosphodiesterase inhibitors and uses thereof | 托帕杜制药公司 | 2024-08-27 | — | — | CN | disclosed |