Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | DAO | P14920 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ATP6V1B1 | P15313 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL98455 | 0.85 | CYP2A6 (1.00) | CYP2A6MAPTDAOKDM4EHPGD | |
| SCHEMBL28124569 | 0.83 | CYP2A6 (0.96) | CYP2A6MAPTDAOKDM4EHPGD | |
| Hydrochloric Acid SCHEMBL28307952 | 0.83 | CYP2A6 (0.96) | CYP2A6MAPTDAOKDM4EHPGD | |
| SCHEMBL28098011 | 0.83 | CYP2A6 (0.96) | CYP2A6MAPTDAOKDM4EHPGD | |
| Water SCHEMBL28244827 | 0.83 | CYP2A6 (0.96) | CYP2A6MAPTDAOKDM4EHPGD | |
| Hydrochloric Acid SCHEMBL28197888 | 0.81 | CYP2A6 (0.92) | CYP2A6MAPTDAOKDM4EHPGD | |
| Bromomethane SCHEMBL28755974 | 0.80 | CYP2A6 (0.89) | CYP2A6MAPTDAOKDM4EHPGD | |
| SCHEMBL1855574 | 0.79 | CYP2A6 (0.54) | CYP2A6MAPTDAOKDM4EHPGD | |
| SCHEMBL28327674 | 0.79 | CYP2A6 (0.79) | CYP2A6MAPTDAOKDM4EHPGD | |
| 2-Methylindole SCHEMBL9817990 | 0.78 | KDM4E (0.50) | MAPTDAOKDM4EHPGDSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4637926-A1 | SYNTHESIS, PHARMACOLOGY AND USE OF NEW WATER-SOLUBLE AND SELECTIVE FMS-LIKE TYROSINE KINASE 3 (FLT3) INHIBITORS | Universität Regensburg (DE) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024132278-A1 | SYNTHESIS, PHARMACOLOGY AND USE OF NEW WATER-SOLUBLE AND SELECTIVE FMS-LIKE TYROSINE KINASE 3 (FLT3) INHIBITORS | UNIVERSITÄT REGENSBURG (DE) | 2024-06-27 | — | — | WO | disclosed |