SCHEMBL31065699

SCHEMBL31065699

C1=Cc2ccncc2OC1

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
STS P08842 1/20 0.38
SIGMAR1 Q99720 1/20 0.33
CA1 P00915 1/20 0.32
CA9 Q16790 1/20 0.32
CYP2B6 P20813 1/20 0.31
CHRNB2 P17787 1/20 0.31
CHRNA4 P43681 1/20 0.31
AAK1 Q2M2I8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4254737 0.84 STS (0.35) STSSIGMAR1CA1CA9CYP2B6
SCHEMBL22124456 0.81 MAOB (0.36) STSCYP2B6AAK1
SCHEMBL15769783 0.79
SCHEMBL9359356 0.79 STS (0.31) STS
SCHEMBL22031973 0.77 STS (0.40) STSCYP2B6
SCHEMBL32679176 0.72 CYP2B6 (0.42) STSCA1CA9CYP2B6
SCHEMBL2289350 0.72 CYP2B6 (0.42) STSCA1CA9CYP2B6
SCHEMBL4889047 0.72 CYP2B6 (0.42) STSCA1CA9CYP2B6
SCHEMBL20537304 0.72 CYP2B6 (0.38) STSCA1CA9CYP2B6
Pyridine SCHEMBL8641597 0.72 CYP2B6 (0.37) STSCYP2B6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118561859-A Alpha-glucosidase inhibitory active compounds and application thereof 中国农业大学 2024-08-30 CN claimed
US-12448390-B1 Compound with α-glucosidase inhibitory activity and application thereof CHINA AGRICULTURAL UNIVERSITY (CN) 2025-10-21 US disclosed
CN-118561859-B Alpha-glucosidase inhibitory active compounds and application thereof 中国农业大学 2024-10-22 CN disclosed
CN-118561859-A Alpha-glucosidase inhibitory active compounds and application thereof 中国农业大学 2024-08-30 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12448390-B1 Compound with α-glucosidase inhibitory activity and application thereof GANAB, GANC, GBA3 STS 443/4885SIGMAR1 4506/4885CA1 2073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.