Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 10/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CPN1 | P15169 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17064410 | 1.00 | KLKB1 (0.43) | KLKB1SIGMAR1MTORRAB9AGRM7 | |
| SCHEMBL17064442 | 0.93 | KLKB1 (0.44) | KLKB1SIGMAR1TACR1 | |
| SCHEMBL31067595 | 0.93 | KLKB1 (0.44) | KLKB1SIGMAR1TACR1 | |
| SCHEMBL22417031 | 0.89 | KLKB1 (0.46) | KLKB1MAPT | |
| SCHEMBL17073494 | 0.89 | KLKB1 (0.43) | KLKB1CYP3A4TDP1 | |
| SCHEMBL17064389 | 0.88 | KLKB1 (0.44) | KLKB1CYP3A4TSHRMEN1KMT2A | |
| SCHEMBL31067579 | 0.88 | KLKB1 (0.44) | KLKB1CYP3A4TSHRMEN1KMT2A | |
| SCHEMBL28260287 | 0.85 | MTOR (0.56) | SIGMAR1MTORRAB9AGRM7TACR1 | |
| SCHEMBL21507490 | 0.85 | KLKB1 (0.45) | KLKB1SIGMAR1TACR1 | |
| SCHEMBL23428922 | 0.84 | TSHR (0.47) | KLKB1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307772-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2024-06-28 | — | — | CN | disclosed |