Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 17/20 | 0.82 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.58 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.40 |
| ▸ | OGFOD1 | Q8N543 | 1/20 | 0.40 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29345989 | 0.96 | CRBN (0.89) | CRBNDDB1TET2OGFOD1TET1 | |
| SCHEMBL31068569 | 0.94 | CRBN (0.72) | CRBNDDB1TET2OGFOD1TET1 | |
| SCHEMBL21496491 | 0.90 | CRBN (1.00) | CRBNDDB1 | |
| SCHEMBL31068539 | 0.90 | CRBN (0.79) | CRBNDDB1TET2OGFOD1TET1 | |
| SCHEMBL31068567 | 0.87 | CRBN (0.68) | CRBNDDB1TET2OGFOD1TET1 | |
| SCHEMBL29346911 | 0.86 | CRBN (0.67) | CRBNDDB1TET2OGFOD1TET1 | |
| SCHEMBL29346959 | 0.84 | CRBN (0.64) | CRBNDDB1TET2OGFOD1TET1 | |
| SCHEMBL29346920 | 0.84 | CRBN (0.69) | CRBNDDB1KMT2A | |
| SCHEMBL31068579 | 0.83 | CRBN (0.68) | CRBNDDB1 | |
| SCHEMBL29346944 | 0.83 | CRBN (0.65) | CRBNDDB1TET2OGFOD1TET1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4650348-A1 | CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR | Mitsubishi Tanabe Pharma Corporation (JP) | 2025-11-19 | — | — | EP | disclosed |
| WO-2024150815-A1 | CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR | 田辺三菱製薬株式会社 | 2024-07-18 | — | — | WO | disclosed |