Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25259285 | 1.00 | KDM4E (0.50) | KDM4ESLC6A4SLC6A2AOC3ADRB3 | |
| SCHEMBL25833472 | 0.84 | SLC6A4 (0.47) | KDM4ESLC6A4SLC6A2AOC3MEN1 | |
| SCHEMBL25857480 | 0.84 | SLC6A4 (0.46) | SLC6A4SLC6A2AOC3SLC6A3 | |
| SCHEMBL25260933 | 0.84 | SLC6A4 (0.46) | SLC6A4SLC6A2AOC3SLC6A3 | |
| SCHEMBL31068777 | 0.81 | SLC6A2 (0.55) | SLC6A4SLC6A2AOC3ADRB3ADRB2 | |
| SCHEMBL25262310 | 0.81 | SLC6A2 (0.55) | SLC6A4SLC6A2AOC3ADRB3ADRB2 | |
| SCHEMBL31664244 | 0.81 | SLC6A2 (0.55) | SLC6A4SLC6A2AOC3ADRB3ADRB2 | |
| SCHEMBL25262299 | 0.80 | SLC6A2 (0.43) | SLC6A4SLC6A2AOC3ADRB3ADRB2 | |
| SCHEMBL31068677 | 0.80 | SLC6A2 (0.43) | SLC6A4SLC6A2AOC3ADRB3ADRB2 | |
| SCHEMBL31068787 | 0.77 | SLC6A2 (0.48) | KDM4ESLC6A4SLC6A2AOC3ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4463453-A1 | AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS | AGV Discovery (FR) | 2024-11-20 | — | — | EP | disclosed |
| CN-118541370-A | Azaindole derivatives and their use as ERK kinase inhibitors | AGV探索公司 | 2024-08-23 | — | — | CN | disclosed |