Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SI | P14410 | 2/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20577612 | 1.00 | TDP1 (0.50) | TDP1MGAMGAASIMGAM2 | |
| SCHEMBL31068996 | 1.00 | TDP1 (0.50) | TDP1MGAMGAASIMGAM2 | |
| SCHEMBL30443221 | 0.98 | TDP1 (0.48) | TDP1MGAMGAASIMGAM2 | |
| SCHEMBL9304208 | 0.92 | MGAM (0.46) | TDP1MGAMGAASIMGAM2 | |
| SCHEMBL22031570 | 0.92 | MGAM (0.46) | TDP1MGAMGAASIMGAM2 | |
| SCHEMBL16116433 | 0.88 | TDP1 (0.41) | TDP1MGAMGAASIMGAM2 | |
| SCHEMBL6403480 | 0.87 | TDP1 (0.40) | TDP1MGAMGAASIMGAM2 | |
| SCHEMBL3615372 | 0.87 | TDP1 (0.40) | TDP1MGAMGAASIMGAM2 | |
| SCHEMBL15905663 | 0.86 | MGAM (0.41) | TDP1MGAMGAASIMGAM2 | |
| SCHEMBL3623614 | 0.86 | TDP1 (0.39) | TDP1MGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066408-A1 | Polyol-Derived Compounds | ARXADA AG (CH) | 2025-02-27 | — | — | US | disclosed |
| US-20240336646-A1 | Polyol-Derived Compounds | ARXADA AG (CH) | 2024-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240336646-A1 | Polyol-Derived Compounds | PARG, SQLE, PARN | TDP1 910/4885MGAM 850/4885GAA 326/4885 |
| US-20250066408-A1 | Polyol-Derived Compounds | PARG, SQLE, PARN | TDP1 910/4885MGAM 850/4885GAA 326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.