SCHEMBL31069147

SCHEMBL31069147

Cc1c(Cl)cccc1O[C@H](C)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.56
TSHR P16473 1/20 0.54
HTR2A P28223 1/20 0.54
HTR2C P28335 1/20 0.54
HTR2B P41595 1/20 0.54
MRGPRX4 Q96LA9 1/20 0.46
HPGD P15428 3/20 0.44
MEN1 O00255 1/20 0.44
PPARG P37231 2/20 0.44
PPARD Q03181 2/20 0.44
PPARA Q07869 2/20 0.44
ALDH1A1 P00352 2/20 0.44
KDM4E B2RXH2 1/20 0.44
HSD17B10 Q99714 1/20 0.44
CYP1A2 P05177 1/20 0.44
GAA P10253 1/20 0.44
CYP2C9 P11712 1/20 0.44
PKM P14618 1/20 0.44
CYP2C19 P33261 1/20 0.44
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6739130 1.00 KMT2A (0.56) KMT2ATSHRHTR2AHTR2CHTR2B
SCHEMBL1576594 0.86 KMT2A (0.59) KMT2ATSHRHTR2AHTR2CHTR2B
SCHEMBL1019372 0.86 KMT2A (0.59) KMT2ATSHRHTR2AHTR2CHTR2B
SCHEMBL12784740 0.85 TSHR (0.59) KMT2ATSHRHTR2AHTR2CHTR2B
SCHEMBL503699 0.84 KMT2A (0.66) KMT2ATSHRHTR2AHTR2CHTR2B
SCHEMBL8935734 0.84 KMT2A (0.66) KMT2ATSHRHTR2AHTR2CHTR2B
SCHEMBL31108086 0.82 KMT2A (0.54) KMT2ATSHRHTR2AHTR2CHTR2B
SCHEMBL12290698 0.80 KMT2A (0.40) KMT2ATSHRHTR2AHTR2CHTR2B
SCHEMBL3949483 0.80 TSHR (0.58) KMT2ATSHRHTR2AHTR2CHTR2B
SCHEMBL10615826 0.80 TSHR (0.58) KMT2ATSHRHTR2AHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12286399-B2 Synthesis of (R)(+)-2-(4-chloro-2-methyl phenoxy)propanoic acid in high enantiomeric excess PATEL FRAMROZE BOMI (US) 2025-04-29 US disclosed
US-20240254069-A1 SYNTHESIS OF (R)(+)-2-(4-CHLORO-2-METHYL PHENOXY)PROPANOIC ACID IN HIGH ENANTIOMERIC EXCESS PATEL FRAMROZE BOMI (US) 2024-08-01 US disclosed