SCHEMBL31069161

SCHEMBL31069161

O=S(=O)(C=Cc1ccccc1)OC(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PPARG P37231 13/20 0.50
NFE2L2 Q16236 3/20 0.50
LMNA P02545 2/20 0.50
PKM P14618 1/20 0.38
KMT2A Q03164 1/20 0.38
ALDH1A1 P00352 2/20 0.35
HTT P42858 1/20 0.35
HSP90AA1 P07900 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1081899 0.76 PPARG (0.40) PPARGNFE2L2LMNAPKMKMT2A
SCHEMBL6719314 0.75 PPARG (0.58) PPARGNFE2L2LMNAALDH1A1HTT
SCHEMBL601077 0.72 PPARG (0.68) PPARGNFE2L2LMNAPKMKMT2A
SCHEMBL4126851 0.71 TDP1 (0.37) LMNAKMT2AALDH1A1HTT
SCHEMBL29069915 0.70 CA1 (0.38) KMT2AALDH1A1
SCHEMBL28452982 0.70 TDP1 (0.36) KMT2AALDH1A1
SCHEMBL28773292 0.70 CA1 (0.38) KMT2AALDH1A1
SCHEMBL8092474 0.70 MAOB (0.35) NFE2L2LMNAALDH1A1
SCHEMBL776987 0.69 CA1 (0.41) PPARGNFE2L2LMNAKMT2AALDH1A1
Ammonia Solution, Strong SCHEMBL29155292 0.69 CA1 (0.37) KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240255852-A1 METHOD FOR MANUFACTURING SEMICONDUCTOR SUBSTRATE AND COMPOSITION JSR CORPORATION (JP) 2024-08-01 US disclosed