Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARG | Q86W56 | 5/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31069305 | 0.89 | CYP3A4 (0.41) | — | |
| SCHEMBL31069388 | 0.89 | PARG (0.38) | PARGHCRTR1HCRTR2DRD2HTR2C | |
| SCHEMBL31069320 | 0.88 | CYP3A4 (0.32) | DRD2HTR2CHRH1 | |
| SCHEMBL31069389 | 0.87 | PARG (0.36) | PARGHCRTR1HCRTR2 | |
| SCHEMBL31069325 | 0.85 | PARG (0.35) | PARG | |
| SCHEMBL31069330 | 0.85 | CYP3A4 (0.36) | PARG | |
| SCHEMBL31069281 | 0.83 | PARG (0.33) | PARG | |
| SCHEMBL31069392 | 0.82 | PARG (0.36) | PARG | |
| SCHEMBL31069408 | 0.80 | CYP3A4 (0.38) | DRD2 | |
| SCHEMBL31069420 | 0.77 | SLC6A2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024174953-A1 | BENZIMIDAZOLE DERIVATIVE AND MEDICAL USE THEREOF | 苏州隆博泰药业有限公司 | 2024-08-29 | — | — | WO | claimed |
| WO-2024174953-A1 | BENZIMIDAZOLE DERIVATIVE AND MEDICAL USE THEREOF | 苏州隆博泰药业有限公司 | 2024-08-29 | — | — | WO | disclosed |