Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | GNRHR | P30968 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 3/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6218923 | 0.89 | CNR2 (0.49) | GRM2BCHEACHECNR2HDAC1 | |
| SCHEMBL6245220 | 0.88 | GRM2 (0.47) | GRM2GNRHRCYP3A4CYP2C19L3MBTL1 | |
| SCHEMBL3734568 | 0.87 | GRM2 (0.46) | GRM2GNRHRCYP3A4CYP2C19L3MBTL1 | |
| SCHEMBL6242216 | 0.86 | GNRHR (0.43) | GRM2GNRHRCYP3A4CYP2C19L3MBTL1 | |
| SCHEMBL6493464 | 0.85 | GRM2 (0.42) | GRM2GNRHRKDM4ECYP1A2CYP3A4 | |
| SCHEMBL31069497 | 0.81 | GNRHR (0.47) | GRM2GNRHRKDM4ECYP1A2CYP3A4 | |
| SCHEMBL22135974 | 0.80 | STING1 (0.52) | MEN1KMT2ACYP3A4CYP2C19L3MBTL1 | |
| SCHEMBL6221079 | 0.80 | CNR2 (0.48) | GNRHRBCHEACHECNR2 | |
| SCHEMBL12635695 | 0.79 | MEN1 (0.66) | MEN1KMT2AKDM4EL3MBTL1RECQL | |
| SCHEMBL7879921 | 0.79 | GNRHR (0.43) | GRM2GNRHRCYP3A4CYP2C19L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024174953-A1 | BENZIMIDAZOLE DERIVATIVE AND MEDICAL USE THEREOF | 苏州隆博泰药业有限公司 | 2024-08-29 | — | — | WO | disclosed |