Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 14/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7488753 | 0.83 | MAPT (0.56) | NTRK1MAPTTDP1SMN1; SMN2LMNA | |
| SCHEMBL14605045 | 0.82 | NTRK1 (0.79) | NTRK1MAPTTDP1SMN1; SMN2LMNA | |
| SCHEMBL7491576 | 0.80 | MAPT (0.51) | NTRK1MAPTTDP1SMN1; SMN2LMNA | |
| SCHEMBL15908733 | 0.76 | MAPT (0.47) | NTRK1MAPTTDP1SMN1; SMN2LMNA | |
| SCHEMBL22939156 | 0.74 | TSHR (0.47) | NTRK1MAPTTDP1SMN1; SMN2LMNA | |
| SCHEMBL7485099 | 0.74 | MAPT (0.56) | MAPTTDP1SMN1; SMN2LMNATSHR | |
| SCHEMBL21822502 | 0.73 | MAPT (0.50) | NTRK1MAPTTDP1SMN1; SMN2LMNA | |
| SCHEMBL15649531 | 0.73 | KDM4E (0.46) | MAPTTDP1SMN1; SMN2LMNATSHR | |
| SCHEMBL2428965 | 0.73 | MEN1 (0.46) | MAPTSMN1; SMN2LMNATSHRKDM4E | |
| SCHEMBL327634 | 0.73 | MAPT (0.51) | MAPTTDP1SMN1; SMN2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024174953-A1 | BENZIMIDAZOLE DERIVATIVE AND MEDICAL USE THEREOF | 苏州隆博泰药业有限公司 | 2024-08-29 | — | — | WO | disclosed |