SCHEMBL31069480

SCHEMBL31069480

CC(C)c1c(-c2ccc(Cl)cc2)[nH]c2nccnc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 17/20 1.00
CCNB2 O95067 16/20 1.00
CCNB1 P14635 16/20 1.00
CCNB3 Q8WWL7 16/20 1.00
GSK3B P49841 16/20 1.00
GSK3A P49840 15/20 1.00
CDK5 Q00535 12/20 1.00
CDK5R1 Q15078 11/20 1.00
GCGR P47871 1/20 0.43
MAPK8 P45983 3/20 0.41
AURKA O14965 2/20 0.41
MAP4K4 O95819 2/20 0.41
PAK4 O96013 2/20 0.41
ABL1 P00519 2/20 0.41
FYN P06241 2/20 0.41
RET P07949 2/20 0.41
KDR P35968 2/20 0.41
CDK8 P49336 2/20 0.41
ACVR1 Q04771 2/20 0.41
PTK2 Q05397 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL490956 1.00 CDK1 (1.00) CDK1CCNB2CCNB1CCNB3GSK3B
SCHEMBL16705135 0.85 GSK3A (0.74) CDK1CCNB2CCNB1CCNB3GSK3B
SCHEMBL1777366 0.84 GSK3A (0.73) CDK1CCNB2CCNB1CCNB3GSK3B
SCHEMBL490964 0.82 CDK1 (1.00) CDK1CCNB2CCNB1CCNB3GSK3B
SCHEMBL490581 0.80 CDK1 (1.00) CDK1CCNB2CCNB1CCNB3GSK3B
SCHEMBL490878 0.71 GSK3A (1.00) CDK1CCNB2CCNB1CCNB3GSK3B
SCHEMBL13950079 0.71 GSK3A (0.60) CDK1CCNB2CCNB1CCNB3GSK3B
SCHEMBL490985 0.70 CDK1 (0.57) CDK1CCNB2CCNB1CCNB3GSK3B
SCHEMBL14506380 0.70 CCNB2 (0.53) CDK1CCNB2CCNB1CCNB3GSK3B
SCHEMBL490764 0.69 GSK3A (1.00) CDK1CCNB2CCNB1CCNB3GSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240252688-A1 COMPOSITIONS AND METHODS FOR ENHANCED PROTEIN PRODUCTION HDT BIO CORP. 2024-08-01 US disclosed