Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.96 |
| ▸ | GAA | P10253 | 4/20 | 0.96 |
| ▸ | MAPT | P10636 | 3/20 | 0.96 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | AOC1 | P19801 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2933468 | 1.00 | KDM4E (0.96) | KDM4EGAAMAPTHDAC1HDAC3 | |
| SCHEMBL541824 | 0.98 | KDM4E (1.00) | KDM4EGAAMAPTHDAC1HDAC3 | |
| SCHEMBL29922301 | 0.98 | KDM4E (1.00) | KDM4EGAAMAPTHDAC1HDAC3 | |
| SCHEMBL5450859 | 0.98 | KDM4E (1.00) | KDM4EGAAMAPTHDAC1HDAC3 | |
| SCHEMBL17874938 | 0.98 | KDM4E (1.00) | KDM4EGAAMAPTHDAC1HDAC3 | |
| SCHEMBL23016005 | 0.98 | KDM4E (1.00) | KDM4EGAAMAPTHDAC1HDAC3 | |
| SCHEMBL20333672 | 0.96 | KDM4E (0.89) | KDM4EGAAMAPTHDAC1HDAC3 | |
| SCHEMBL720368 | 0.91 | MAPT (0.81) | KDM4EGAAMAPTHDAC1HDAC3 | |
| SCHEMBL30657522 | 0.91 | MAPT (0.81) | KDM4EGAAMAPTHDAC1HDAC3 | |
| Hydrochloric Acid SCHEMBL28010549 | 0.89 | MAPT (0.78) | KDM4EGAAMAPTHDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118580225-A | PRMT5-MTA synergistic inhibitor and application thereof | 甘李药业股份有限公司 | 2024-09-03 | — | — | CN | disclosed |