Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 3/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | PAK4 | O96013 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25380687 | 1.00 | TNIK (0.40) | TNIKSCN1ASCN4AKCNH2SCN5A | |
| SCHEMBL23761157 | 0.87 | TNIK (0.41) | TNIKSCN1ASCN4AKCNH2SCN5A | |
| SCHEMBL31069722 | 0.85 | TNIK (0.41) | TNIKSCN1ASCN4AKCNH2SCN5A | |
| SCHEMBL31069733 | 0.85 | TNIK (0.48) | TNIKSCN1ASCN4AKCNH2SCN5A | |
| SCHEMBL31069734 | 0.85 | TNIK (0.40) | TNIKSCN1ASCN4AKCNH2SCN5A | |
| SCHEMBL25379735 | 0.85 | TNIK (0.48) | TNIKSCN1ASCN4AKCNH2SCN5A | |
| SCHEMBL25380728 | 0.85 | TNIK (0.40) | TNIKSCN1ASCN4AKCNH2SCN5A | |
| SCHEMBL25380390 | 0.85 | TNIK (0.41) | TNIKSCN1ASCN4AKCNH2SCN5A | |
| SCHEMBL25380642 | 0.85 | TNIK (0.39) | TNIKSCN1ASCN4AKCNH2SCN5A | |
| SCHEMBL31069732 | 0.85 | TNIK (0.39) | TNIKSCN1ASCN4AKCNH2SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118556044-A | Fused heterocyclic compound, preparation method thereof and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2024-08-27 | — | — | CN | disclosed |