SCHEMBL31070706

SCHEMBL31070706

O=C1CCC(N2Cc3cc(OC4CC5(CCNCC5)C4)ccc3C2=O)C(=O)N1

nearest known ligand 0.60

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 10/20 0.60
▸ IKZF2 Q9UKS7 7/20 0.49
▸ CSNK1A1 P48729 1/20 0.48
▸ WIZ O95785 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24816763 0.94 CRBN (0.58) CRBNIKZF2CSNK1A1WIZ
SCHEMBL31070691 0.92 CRBN (0.60) CRBNIKZF2CSNK1A1WIZ
SCHEMBL20234306 0.89 CRBN (0.65) CRBNIKZF2CSNK1A1WIZ
SCHEMBL30273536 0.89 CRBN (0.65) CRBNIKZF2CSNK1A1WIZ
SCHEMBL20046231 0.89 CRBN (0.65) CRBNIKZF2CSNK1A1WIZ
SCHEMBL22291438 0.88 IKZF2 (0.52) CRBNIKZF2WIZ
SCHEMBL30183833 0.88 IKZF2 (0.52) CRBNIKZF2WIZ
SCHEMBL20231474 0.86 CRBN (0.67) CRBNIKZF2CSNK1A1WIZ
SCHEMBL20046262 0.86 CRBN (0.67) CRBNIKZF2CSNK1A1WIZ
SCHEMBL31070701 0.85 CRBN (0.61) CRBNIKZF2CSNK1A1WIZ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118556048-A Sulfur/oxygen substituted glutarimide isoindolinone skeleton-based compound and application thereof 标新生物医药科技(上海)有限公司 2024-08-27 — — CN claimed
CN-118556048-A Sulfur/oxygen substituted glutarimide isoindolinone skeleton-based compound and application thereof 标新生物医药科技(上海)有限公司 2024-08-27 — — CN disclosed
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