Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 0.63 |
| ▸ | BTK | Q06187 | 9/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31071077 | 0.95 | EGFR (0.61) | EGFRBTK | |
| SCHEMBL31071061 | 0.91 | EGFR (0.64) | EGFRBTK | |
| SCHEMBL31071127 | 0.89 | EGFR (0.63) | EGFRBTK | |
| SCHEMBL31071260 | 0.88 | EGFR (0.62) | EGFRBTK | |
| SCHEMBL31071171 | 0.88 | EGFR (0.61) | EGFRBTK | |
| SCHEMBL31071190 | 0.86 | EGFR (0.61) | EGFRBTK | |
| SCHEMBL31071084 | 0.86 | EGFR (0.63) | EGFRBTK | |
| SCHEMBL31071187 | 0.86 | EGFR (0.61) | EGFRBTK | |
| SCHEMBL31071114 | 0.86 | EGFR (0.61) | EGFRBTK | |
| SCHEMBL31071251 | 0.86 | EGFR (0.63) | EGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240294531-A1 | COVALENT HETEROCYCLES AND USES THEREOF | KUMQUAT BIOSCIENCES INC. | 2024-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240294531-A1 | COVALENT HETEROCYCLES AND USES THEREOF | TP53, KRAS, CHEK2 | EGFR 154/4885BTK 36/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.