Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | APLNR | P35414 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31071934 | 1.00 | CFTR (0.42) | CFTRAPLNRKDM4ELMNASLC6A2 | |
| SCHEMBL21780595 | 1.00 | CFTR (0.42) | CFTRAPLNRKDM4ELMNASLC6A2 | |
| SCHEMBL21767551 | 1.00 | CFTR (0.42) | CFTRAPLNRKDM4ELMNASLC6A2 | |
| SCHEMBL21767420 | 1.00 | CFTR (0.42) | CFTRAPLNRKDM4ELMNASLC6A2 | |
| SCHEMBL29429452 | 1.00 | CFTR (0.42) | CFTRAPLNRKDM4ELMNASLC6A2 | |
| SCHEMBL21767410 | 0.96 | CFTR (0.45) | CFTRAPLNRKDM4ELMNASLC6A2 | |
| SCHEMBL31071992 | 0.96 | CFTR (0.45) | CFTRAPLNRKDM4ELMNASLC6A2 | |
| SCHEMBL21767407 | 0.85 | PTGDR2 (0.40) | CFTRKDM4ELMNAHPGDCYP1A2 | |
| SCHEMBL21767405 | 0.85 | PTGDR2 (0.40) | CFTRKDM4ELMNAHPGDCYP1A2 | |
| SCHEMBL21767595 | 0.85 | PTGDR2 (0.40) | CFTRKDM4ELMNAHPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118878533-A | Inhibition of αvβ6 integrin | 莫菲克医疗股份有限公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-112805001-B | Inhibition of αvβ6 integrin | 莫菲克医疗股份有限公司 | 2024-07-23 | — | — | CN | disclosed |