SCHEMBL3107265

SCHEMBL3107265

Oc1cccc(-c2cc3cc4nc(cc5ccc(cc6nc(cc2[nH]3)C=C6)[nH]5)C=C4)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MGAM O43451 1/20 0.41
▸ GAA P10253 1/20 0.41
▸ SI P14410 1/20 0.41
▸ MGAM2 Q2M2H8 1/20 0.41
▸ STAT3 P40763 1/20 0.41
▸ STAT1 P42224 1/20 0.41
▸ PTPN1 P18031 1/20 0.41
▸ MAPK13 O15264 1/20 0.39
▸ RAF1 P04049 1/20 0.39
▸ BRAF P15056 1/20 0.39
▸ MAPK12 P53778 1/20 0.39
▸ MAPK11 Q15759 1/20 0.39
▸ MAPK14 Q16539 1/20 0.39
▸ BRDT Q58F21 1/20 0.39
▸ MAPT P10636 1/20 0.38
▸ RXFP1 Q9HBX9 1/20 0.38
▸ PARP1 P09874 1/20 0.38
▸ HSD17B1 P14061 5/20 0.37
▸ HSD17B2 P37059 5/20 0.37
▸ AURKA O14965 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3237435 0.92 MGAM (0.36) MGAMGAASIMGAM2STAT3
SCHEMBL28590232 0.87 STAT3 (0.38) STAT3STAT1
SCHEMBL28586570 0.86 STAT3 (0.37) STAT3STAT1
SCHEMBL3352970 0.84 STAT3 (0.38) MGAMGAASIMGAM2STAT3
SCHEMBL29960178 0.84 STAT3 (0.38) MGAMGAASIMGAM2STAT3
SCHEMBL29827170 0.84 STAT3 (0.52) MGAMGAASTAT3STAT1MAPT
SCHEMBL473160 0.84 STAT3 (0.52) MGAMGAASTAT3STAT1MAPT
Benzene SCHEMBL28628071 0.84 STAT3 (0.52) MGAMGAASTAT3STAT1MAPT
SCHEMBL28557685 0.83 STAT3 (0.41) STAT3STAT1MAPK14MAPTADORA1
SCHEMBL28751479 0.83 NPC1 (0.43) GAASTAT3STAT1MAPTPARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119223945-A High-temperature Daqu liquor identification method based on porphyrin catalyst quasi-peroxidase activity oxidation TMB color change 中南民族大学 2024-12-31 — — CN claimed
CN-118555971-A Amorphous photosensitive particles, methods of making and methods of using the same 马里兰大学帕克分校 2024-08-27 — — CN claimed
CN-112940268-B Interface in-situ growth metal-organic framework material and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2022-04-12 — — CN claimed
CN-112940268-A Interface in-situ growth metal-organic framework material and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2021-06-11 — — CN claimed
US-9211283-B2 Nanoparticle carrier systems based on human serum albumin for photodynamic therapy BIOLITEC PHARMA MARKETING LTD (MY) 2015-12-15 — — US claimed
CN-102740875-A Human serum albumin-based nanoparticle carrier system for photodynamic therapy BIOLITEC INC 2012-10-17 — — CN claimed
CN-102740892-A Poly (DL-lactic-co-glycolic acid) (PLGA) -based nanoparticle carrier system for photodynamic therapy (PDT) BIOLITEC INC 2012-10-17 — — CN claimed
CN-102167703-A Flexible multi-arm porphyrin with pyridine groups and synthesis method thereof UNIV NORTHWEST NORMAL 2011-08-31 — — CN claimed
CN-1754097-A Active oxygen species measuring device YUASA MAKOTO (JP) 2006-03-29 — — CN claimed
CN-1605026-A Electrode for active oxygen species and sensor using the electrode MAKOTO YUASA (JP) 2005-04-06 — — CN claimed
EP-1263761-B1 COMPOUNDS FOR PDT BIOLITEC PHARMA MARKETING LTD (MY) 2004-12-01 — — EP claimed
CN-1226147-A Method for inproving selectivity in photo-activation and detection of molecular diagnosis agents PHOTOGEN INC (US) 1999-08-18 — — CN claimed
CN-1226148-A Method for improving light activation selectivity of molecular reagent PHOTOGEN INC (US) 1999-08-18 — — CN claimed
EP-0337601-B1 PORPHYRINS AND MEDICAMENTS FOR CANCER TREATMENT SCOTIA HOLDINGS PLC (GB) 1993-05-05 — — EP claimed
CN-119223945-A High-temperature Daqu liquor identification method based on porphyrin catalyst quasi-peroxidase activity oxidation TMB color change 中南民族大学 2024-12-31 — — CN disclosed
CN-118555971-A Amorphous photosensitive particles, methods of making and methods of using the same 马里兰大学帕克分校 2024-08-27 — — CN disclosed
CN-117396611-A Method for delivering a cargo into a cell 成思有限责任公司 2024-01-12 — — CN disclosed
CN-1226147-A Method for inproving selectivity in photo-activation and detection of molecular diagnosis agents PHOTOGEN INC (US) 1999-08-18 — — CN disclosed
EP-0820305-A2 CANCER TREATMENT BY PHOTODYNAMIC THERAPY, IN COMBINATION WITH AN IMMUNOADJUVANT Wound Healing of Oklahoma (US) 1998-01-28 — — EP disclosed
WO-1996031237-A2 CANCER TREATMENT BY PHOTODYNAMIC THERAPY, IN COMBINATION WITH AN IMMUNOADJUVANT WOUND HEALING OF OKLAHOMA (US) 1996-10-10 — — WO disclosed
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