Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5411654 | 0.81 | GRM6 (0.40) | GRM6EGFRCISD2ALDH1A1MEN1 | |
| SCHEMBL168008 | 0.80 | MAPT (0.40) | NPSR1ALDH1A1MEN1KMT2ACA12 | |
| SCHEMBL20263505 | 0.79 | NPC1 (0.39) | GRM6LCKCISD2CYP2C9CYP2C19 | |
| SCHEMBL20269597 | 0.77 | GAA (0.49) | CYP2C9CYP2C19ALDH1A1MEN1NPC1 | |
| SCHEMBL365155 | 0.74 | DAO (0.42) | LCKALDH1A1GSK3BMEN1NPC1 | |
| SCHEMBL13171452 | 0.74 | CA12 (0.39) | LCKEGFRCYP2C9CYP2C19NPSR1 | |
| SCHEMBL5425234 | 0.73 | KDM4E (0.36) | CYP2C9CYP2C19NPSR1ALDH1A1NPC1 | |
| SCHEMBL828580 | 0.72 | EGFR (0.41) | EGFRCYP2C9CYP2C19NPSR1ALDH1A1 | |
| SCHEMBL20263529 | 0.72 | GSK3B (0.40) | GRM6LCKEGFRCISD2CYP2C9 | |
| SCHEMBL22774665 | 0.72 | LCK (0.43) | LCKCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024173646-A1 | CYCLIN-DEPENDENT KINASE DEGRADING COMPOUNDS | INNOVO THERAPEUTICS, INC. (US) | 2024-08-22 | — | — | WO | disclosed |