SCHEMBL31074734

SCHEMBL31074734

N=C(N)NCCC[C@@H](NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)O

nearest known ligand 0.54

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 14/20 0.54
▸ NPY1R P25929 8/20 0.54
▸ NPY5R Q15761 6/20 0.54
▸ NPY2R P49146 5/20 0.54
▸ KISS1R Q969F8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31074830 1.00 NPY4R (0.54) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL29534175 1.00 NPY4R (0.54) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL7592903 0.95 NPY4R (0.53) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL7592909 0.95 NPY4R (0.53) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL29419547 0.95 NPY4R (0.53) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL13449160 0.94 NPY4R (0.60) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL30988894 0.94 NPY4R (0.64) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL13448837 0.92 NPY4R (0.52) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL30437446 0.92 NPY4R (0.52) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL29533534 0.91 NPY4R (0.54) NPY4RNPY1RNPY5RNPY2RKISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240287154-A1 MC3R AGONIST PEPTIDES COURAGE THERAPEUTICS, INC. 2024-08-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240287154-A1 MC3R AGONIST PEPTIDES MC3R, MC4R, MC1R NPY4R 15/4885NPY1R 19/4885NPY5R 47/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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