SCHEMBL31075950

SCHEMBL31075950

CN(CCCCc1ccc2c(n1)NCCC2)[C@H]1CCNC1

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ITGAV P06756 20/20 0.50
ITGB3 P05106 11/20 0.50
ITGB5 P18084 4/20 0.50
ITGB6 P18564 12/20 0.48
ITGA5 P08648 6/20 0.46
ITGB8 P26012 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31076035 1.00 ITGAV (0.50) ITGAVITGB3ITGB5ITGB6ITGA5
SCHEMBL31075661 0.99 ITGAV (0.49) ITGAVITGB3ITGB5ITGB6ITGA5
SCHEMBL31075798 0.99 ITGAV (0.49) ITGAVITGB3ITGB5ITGB6ITGA5
SCHEMBL31075931 0.87 ITGAV (0.48) ITGAVITGB3ITGB5ITGB6ITGA5
SCHEMBL31075739 0.87 ITGAV (0.44) ITGAVITGB3ITGB5ITGB6
SCHEMBL31075922 0.86 ITGAV (0.49) ITGAVITGB3ITGB5ITGB6ITGA5
SCHEMBL31076042 0.86 ITGAV (0.49) ITGAVITGB3ITGB5ITGB6ITGA5
SCHEMBL31075939 0.86 ITGAV (0.47) ITGAVITGB3ITGB5ITGB6ITGA5
SCHEMBL31075738 0.85 ITGAV (0.43) ITGAVITGB3ITGB5ITGB6ITGA5
SCHEMBL31075918 0.85 ITGAV (0.46) ITGAVITGB3ITGB5ITGB6ITGA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4665458-A1 INHIBITING ALPHA V BETA8 INTEGRIN Morphic Therapeutic, Inc. (US) 2025-12-24 EP disclosed
WO-2024173572-A1 INHIBITING α vβ8 INTEGRIN MORPHIC THERAPEUTIC, INC. (US) 2024-08-22 WO disclosed