SCHEMBL31076215

SCHEMBL31076215

CC(C)(C)[Si](OCCC#CCC#CCCCO)(c1ccccc1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SMYD2 Q9NRG4 2/20 0.33
CYP3A4 P08684 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12988363 0.92 CYP3A4 (0.36) SMYD2CYP3A4HTTSMN1; SMN2
SCHEMBL31520986 0.88 SMYD2 (0.35) SMYD2CYP3A4HTTSMN1; SMN2
SCHEMBL12989590 0.86 CYP3A4 (0.36) SMYD2CYP3A4HTTSMN1; SMN2
SCHEMBL15644069 0.85 CYP3A4 (0.35) SMYD2CYP3A4HTTSMN1; SMN2
SCHEMBL12989787 0.85 CYP3A4 (0.35) SMYD2CYP3A4HTTSMN1; SMN2
SCHEMBL15643694 0.85 CYP3A4 (0.35) SMYD2CYP3A4HTTSMN1; SMN2
SCHEMBL19331784 0.85 CYP3A4 (0.35) SMYD2CYP3A4HTTSMN1; SMN2
SCHEMBL15644046 0.85 CYP3A4 (0.35) SMYD2CYP3A4HTTSMN1; SMN2
SCHEMBL13093647 0.85 SMYD2 (0.35) SMYD2CYP3A4HTTSMN1; SMN2
SCHEMBL13778495 0.82 SMYD2 (0.34) SMYD2CYP3A4HTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024172932-A1 ENDOCANNABINOID LIGANDS AND RELATED ANALOGS NORTHEASTERN UNIVERSITY (US) 2024-08-22 WO disclosed