Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20446514 | 0.86 | HSD17B10 (0.39) | HSD17B10SMN1; SMN2CHRM2CHRM1CHRM3 | |
| SCHEMBL15718593 | 0.86 | HSD17B10 (0.39) | HSD17B10SMN1; SMN2CHRM2CHRM1CHRM3 | |
| SCHEMBL19066055 | 0.86 | HSD17B10 (0.39) | HSD17B10SMN1; SMN2CHRM2CHRM1CHRM3 | |
| SCHEMBL2126924 | 0.82 | HSD17B10 (0.45) | HSD17B10SMN1; SMN2HSD11B1NPC1EPHX2 | |
| SCHEMBL31148270 | 0.82 | HSD17B10 (0.45) | HSD17B10SMN1; SMN2HSD11B1NPC1EPHX2 | |
| SCHEMBL10215476 | 0.82 | HSD17B10 (0.45) | HSD17B10SMN1; SMN2HSD11B1NPC1EPHX2 | |
| SCHEMBL31078106 | 0.81 | HSD17B10 (0.39) | HSD17B10SMN1; SMN2HSD11B1CHRM2CHRM1 | |
| SCHEMBL30484715 | 0.81 | ATM (0.32) | HSD11B1 | |
| SCHEMBL14488388 | 0.80 | HSD17B10 (0.46) | HSD17B10SMN1; SMN2HSD11B1NPC1EPHX2 | |
| SCHEMBL16824583 | 0.80 | HSD17B10 (0.46) | HSD17B10SMN1; SMN2HSD11B1NPC1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240294534-A1 | IMIDAZOTRIAZINE DERIVATIVES AS IL-17 MODULATORS | UCB Biopharma SRL (BE) | 2024-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240294534-A1 | IMIDAZOTRIAZINE DERIVATIVES AS IL-17 MODULATORS | IL17A, IL2, IL15 | HSD17B10 519/4885SMN1; SMN2 3456/4885HSD11B1 242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.