Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.37 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31194365 | 0.86 | BRD4 (0.42) | HSD17B10KDM4ERAB9ASMN1; SMN2BRD4 | |
| SCHEMBL4146607 | 0.81 | BRD4 (0.44) | BRD4APPKIF11METAP2KCNH2 | |
| SCHEMBL9999435 | 0.76 | PARP1 (0.49) | HSD17B10KDM4E | |
| SCHEMBL15058364 | 0.75 | AHR (0.45) | KDM4EBRD4APPTRPA1PIK3C3 | |
| SCHEMBL26823824 | 0.74 | BRD4 (0.39) | BRD4APPPIK3C3 | |
| SCHEMBL22803967 | 0.73 | EPHX2 (0.55) | RAB9AMAPT | |
| SCHEMBL15058223 | 0.72 | AHR (0.47) | KDM4EBRD4APPPIK3C3 | |
| SCHEMBL29745271 | 0.72 | MAPT (0.57) | KDM4ES1PR1MAPT | |
| SCHEMBL1265563 | 0.72 | MAPT (0.57) | KDM4ES1PR1MAPT | |
| SCHEMBL19250504 | 0.72 | DYRK1A (0.53) | KDM4ERAB9ASMN1; SMN2METAP2TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175557-A1 | CYCLOPROPYL-(HETERO)ARYL-SUBSTITUTED ETHYL-SULFOXIME-PYRIDINE DERIVATIVES | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2024-08-29 | — | — | WO | disclosed |
| CN-118359634-A | Pyrazole derivative and medical use thereof | 正大天晴药业集团股份有限公司 | 2024-07-19 | — | — | CN | disclosed |