Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | BUB1 | O43683 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31105397 | 1.00 | GRIN2B (0.40) | GRIN2BGRIN2CUSP2SMN1; SMN2CTSK | |
| SCHEMBL6632443 | 0.90 | GRIN2B (0.46) | GRIN2BGRIN2CUSP2SMN1; SMN2CTSK | |
| SCHEMBL14234512 | 0.90 | GRIN2B (0.46) | GRIN2BGRIN2CUSP2SMN1; SMN2CTSK | |
| SCHEMBL15125135 | 0.90 | GRIN2B (0.46) | GRIN2BGRIN2CUSP2SMN1; SMN2CTSK | |
| SCHEMBL20054323 | 0.89 | GRIN2B (0.43) | GRIN2BGRIN2CUSP2SMN1; SMN2CTSK | |
| SCHEMBL11954515 | 0.85 | USP2 (0.38) | GRIN2BGRIN2CUSP2SMN1; SMN2CTSK | |
| SCHEMBL11954522 | 0.85 | USP2 (0.38) | GRIN2BGRIN2CUSP2SMN1; SMN2CTSK | |
| SCHEMBL31078891 | 0.85 | USP2 (0.38) | GRIN2BGRIN2CUSP2SMN1; SMN2CTSK | |
| SCHEMBL6078246 | 0.84 | USP2 (0.40) | GRIN2BGRIN2CUSP2SMN1; SMN2CTSK | |
| SCHEMBL7227763 | 0.84 | USP2 (0.40) | GRIN2BGRIN2CUSP2SMN1; SMN2CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4651872-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE TO TREAT HYPOPARATHYROIDISM AND OSTEOPOROSIS | Septerna, Inc. (US) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024155601-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE TO TREAT HYPOPARATHYROIDISM AND OSTEOPOROSIS | SEPTERNA, INC. (US) | 2024-07-25 | — | — | WO | disclosed |