Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25424710 | 1.00 | POLB (0.55) | POLBTP53LMNASMN1; SMN2LDHA | |
| SCHEMBL25229814 | 0.96 | TP53 (0.54) | POLBTP53LMNASMN1; SMN2LDHA | |
| SCHEMBL31038304 | 0.96 | TP53 (0.54) | POLBTP53LMNASMN1; SMN2LDHA | |
| SCHEMBL25423218 | 0.89 | POLB (0.54) | POLBTP53LMNASMN1; SMN2LDHA | |
| SCHEMBL25424713 | 0.87 | MEN1 (0.42) | POLBTP53LDHAMEN1KMT2A | |
| SCHEMBL14686719 | 0.86 | TP53 (0.51) | POLBTP53LMNASMN1; SMN2PDE4A | |
| SCHEMBL25276232 | 0.83 | APEX1 (0.41) | POLBTP53SMN1; SMN2MEN1KMT2A | |
| SCHEMBL15668570 | 0.77 | POLB (0.59) | POLBTP53SMN1; SMN2CA1CA2 | |
| SCHEMBL22033300 | 0.76 | POLB (0.48) | POLBTP53CA1CA2CA6 | |
| SCHEMBL25423223 | 0.76 | POLB (0.42) | POLBTP53LMNASMN1; SMN2LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118647606-A | Benzothiophene derivatives as RXFP1 agonists | 百时美施贵宝公司 | 2024-09-13 | — | — | CN | disclosed |