SCHEMBL31079744

SCHEMBL31079744

CNC(=O)c1cc(Nc2nc(Br)cc3ncn(C4CC4)c23)ccc1C

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAP4K1 Q92918 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23243652 1.00 MAP4K1 (0.56) MAP4K1
SCHEMBL23243181 0.90 MAP4K1 (0.56) MAP4K1
SCHEMBL31079922 0.90 MAP4K1 (0.56) MAP4K1
SCHEMBL31079729 0.90 MAP4K1 (0.55) MAP4K1
SCHEMBL23243514 0.90 MAP4K1 (0.55) MAP4K1
SCHEMBL23243531 0.83 MAP4K1 (0.52) MAP4K1
SCHEMBL31036187 0.83 MAP4K1 (0.54) MAP4K1
SCHEMBL23243590 0.83 MAP4K1 (0.54) MAP4K1
SCHEMBL31079905 0.83 MAP4K1 (0.52) MAP4K1
SCHEMBL23243431 0.82 MAP4K1 (0.56) MAP4K1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113227089-B Substituted 6-azabenzimidazole compounds as HPK1 inhibitors 吉利德科学公司 2024-07-05 CN disclosed