Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 15/20 | 0.45 |
| ▸ | ABL1 | P00519 | 2/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | TEK | Q02763 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23243099 | 1.00 | MAP4K1 (0.45) | MAP4K1ABL1JAK1BTKAURKA | |
| SCHEMBL23243506 | 0.91 | MAP4K1 (0.46) | MAP4K1ABL1JAK1 | |
| SCHEMBL31079881 | 0.91 | MAP4K1 (0.46) | MAP4K1ABL1JAK1 | |
| SCHEMBL31079768 | 0.90 | MAP4K1 (0.46) | MAP4K1ABL1JAK1KDR | |
| SCHEMBL23243241 | 0.90 | MAP4K1 (0.46) | MAP4K1ABL1JAK1KDR | |
| SCHEMBL31079766 | 0.90 | MAP4K1 (0.46) | MAP4K1ABL1JAK1KDR | |
| SCHEMBL23243431 | 0.89 | MAP4K1 (0.56) | MAP4K1 | |
| SCHEMBL31079942 | 0.89 | MAP4K1 (0.56) | MAP4K1 | |
| SCHEMBL23243514 | 0.81 | MAP4K1 (0.55) | MAP4K1 | |
| SCHEMBL31079729 | 0.81 | MAP4K1 (0.55) | MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227089-B | Substituted 6-azabenzimidazole compounds as HPK1 inhibitors | 吉利德科学公司 | 2024-07-05 | — | — | CN | disclosed |