⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28142693 | 0.82 | — | — | |
| SCHEMBL31099146 | 0.78 | — | — | |
| SCHEMBL29366973 | 0.73 | — | — | |
| SCHEMBL31375430 | 0.68 | — | — | |
| SCHEMBL27553143 | 0.67 | — | — | |
| SCHEMBL31464151 | 0.65 | — | — | |
| SCHEMBL28142725 | 0.65 | — | — | |
| SCHEMBL28320516 | 0.65 | GRM6 (0.32) | — | |
| SCHEMBL27494759 | 0.65 | — | — | |
| SCHEMBL8763333 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227089-B | Substituted 6-azabenzimidazole compounds as HPK1 inhibitors | 吉利德科学公司 | 2024-07-05 | — | — | CN | disclosed |