Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365953 | 1.00 | SOS1 (0.50) | SOS1LMNATSHRNPSR1NOTUM | |
| SCHEMBL1044961 | 0.92 | SOS1 (0.46) | SOS1LMNATSHRNPSR1NOTUM | |
| SCHEMBL31394743 | 0.90 | SOS1 (0.51) | SOS1LMNATSHRNPSR1NOTUM | |
| SCHEMBL14349262 | 0.89 | SOS1 (0.50) | SOS1LMNATSHRNPSR1NOTUM | |
| SCHEMBL1977588 | 0.85 | CA1 (0.49) | SOS1LMNATSHRNPSR1NOTUM | |
| SCHEMBL20571340 | 0.85 | SOS1 (0.48) | SOS1LMNATSHRNPSR1NOTUM | |
| SCHEMBL31565672 | 0.85 | SOS1 (0.48) | SOS1LMNATSHRNPSR1NOTUM | |
| SCHEMBL3411975 | 0.85 | SOS1 (0.48) | SOS1LMNATSHRNPSR1NOTUM | |
| SCHEMBL2316462 | 0.85 | SOS1 (0.48) | SOS1LMNATSHRNPSR1NOTUM | |
| SCHEMBL30012638 | 0.85 | SOS1 (0.48) | SOS1LMNATSHRNPSR1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227089-B | Substituted 6-azabenzimidazole compounds as HPK1 inhibitors | 吉利德科学公司 | 2024-07-05 | — | — | CN | disclosed |