Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.40 |
| ▸ | ABL1 | P00519 | 9/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31079882 | 1.00 | MAP4K1 (0.40) | MAP4K1ABL1P2RX3KDRCYP1A2 | |
| SCHEMBL23243575 | 1.00 | MAP4K1 (0.40) | MAP4K1ABL1P2RX3KDRCYP1A2 | |
| SCHEMBL31079768 | 0.83 | MAP4K1 (0.46) | MAP4K1ABL1P2RX3KDRCYP1A2 | |
| SCHEMBL31079766 | 0.83 | MAP4K1 (0.46) | MAP4K1ABL1P2RX3KDRCYP1A2 | |
| SCHEMBL23243241 | 0.83 | MAP4K1 (0.46) | MAP4K1ABL1P2RX3KDRCYP1A2 | |
| SCHEMBL28603741 | 0.80 | MAP4K1 (0.36) | MAP4K1ABL1 | |
| SCHEMBL25201920 | 0.76 | ABL1 (0.35) | ABL1KDRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23243506 | 0.72 | MAP4K1 (0.46) | MAP4K1ABL1 | |
| SCHEMBL31079881 | 0.72 | MAP4K1 (0.46) | MAP4K1ABL1 | |
| SCHEMBL23243431 | 0.72 | MAP4K1 (0.56) | MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227089-B | Substituted 6-azabenzimidazole compounds as HPK1 inhibitors | 吉利德科学公司 | 2024-07-05 | — | — | CN | disclosed |