Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26081242 | 0.79 | HTT (0.41) | TSHRNUDT1ALDH1A1HSD17B10CASP1 | |
| SCHEMBL3598344 | 0.75 | TSHR (0.53) | TSHRNUDT1ALDH1A1HSD17B10CASP1 | |
| SCHEMBL26645844 | 0.74 | KDM4E (0.52) | TSHRALDH1A1HSD17B10KMT2AMEN1 | |
| SCHEMBL21224540 | 0.73 | TSHR (0.41) | TSHRALDH1A1HSD17B10CA12CA1 | |
| SCHEMBL29421611 | 0.73 | TSHR (0.41) | TSHRALDH1A1HSD17B10CA12CA1 | |
| SCHEMBL5767934 | 0.73 | TSHR (0.52) | TSHRNUDT1ALDH1A1HSD17B10CASP1 | |
| SCHEMBL160323 | 0.73 | TSHR (0.52) | TSHRNUDT1ALDH1A1HSD17B10CASP1 | |
| SCHEMBL31316179 | 0.73 | TSHR (0.52) | TSHRNUDT1ALDH1A1HSD17B10CASP1 | |
| SCHEMBL4763799 | 0.73 | TSHR (0.52) | TSHRNUDT1ALDH1A1HSD17B10CASP1 | |
| SCHEMBL12279519 | 0.73 | CSNK1D (0.45) | TSHRALDH1A1HSD17B10SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024182788-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2024-09-06 | — | — | WO | disclosed |