Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL823267 | 1.00 | TLR4 (0.69) | TLR4ALDH1A1MAPTCA1CA2 | |
| SCHEMBL11718459 | 0.87 | TLR4 (0.68) | TLR4CYP19A1 | |
| SCHEMBL14401277 | 0.80 | TLR4 (0.50) | TLR4ALDH1A1MAPTMMP2 | |
| SCHEMBL11181948 | 0.70 | TLR4 (0.47) | TLR4ALDH1A1MAPTMMP2CYP19A1 | |
| SCHEMBL9609547 | 0.68 | TLR4 (0.50) | TLR4ALDH1A1MAPTKMT2A | |
| SCHEMBL5201714 | 0.68 | TLR4 (0.55) | TLR4MAPTCA1CA2CA4 | |
| SCHEMBL2577011 | 0.68 | TLR4 (0.42) | TLR4ALDH1A1MMP2CYP19A1 | |
| SCHEMBL11164098 | 0.67 | TLR4 (0.53) | TLR4ALDH1A1MAPT | |
| SCHEMBL11165151 | 0.67 | TLR4 (0.45) | TLR4ALDH1A1MAPTKMT2A | |
| SCHEMBL1964176 | 0.67 | TLR4 (0.48) | TLR4MAPTCA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118388576-A | Synthesis method of cyclopamine | 四川大学 | 2024-07-26 | — | — | CN | disclosed |