Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.44 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.39 |
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | AKT2 | P31751 | 1/20 | 0.39 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4780743 | 0.87 | TOP1 (0.44) | CCNB2CDK1CCNB1CDK5CDK5R1 | |
| SCHEMBL3230114 | 0.83 | CCNB2 (0.63) | CCNB2CDK1CCNB1CDK5CDK5R1 | |
| SCHEMBL10366831 | 0.82 | CCNB2 (0.46) | CCNB2CDK1CCNB1CDK5CDK5R1 | |
| SCHEMBL6479634 | 0.82 | AHR (0.50) | CCNB2CDK1CCNB1CDK5CDK5R1 | |
| SCHEMBL6478532 | 0.81 | CCNB2 (0.49) | CCNB2CDK1CCNB1CDK5CDK5R1 | |
| SCHEMBL4781475 | 0.79 | NPC1 (0.49) | CCNB2CDK1CCNB1CDK5CDK5R1 | |
| SCHEMBL14291446 | 0.78 | CCNB2 (0.43) | CCNB2CDK1CCNB1CDK5CDK5R1 | |
| SCHEMBL18741104 | 0.77 | MAPT (0.49) | CCNB2CDK1CCNB1CDK5CDK5R1 | |
| SCHEMBL28542030 | 0.76 | CDC7 (0.47) | KDM4EKMT2AALDH1A1ATMCYP1A2 | |
| SCHEMBL28259496 | 0.75 | KMT2A (0.69) | KDM4EKMT2AALDH1A1ATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115108960-B | Preparation method and application of polysubstituted indole compound | 陕西蒲城万德科技有限公司 | 2024-08-27 | — | — | CN | disclosed |